Insecticidal Proteins: From Discovery to Commercialization

Sponsored By: 

Organizer(s)

• 

  William Moar (he/him/his)

  Regulatory Science
  Bayer Crop Science
  Chesterfield, Missouri
• 

  Mark Nelson

  Trait Discovery
  Corteva Agriscience
  Johnston, Iowa
• KG

  Kara Giddings

  Bayer CropScience
  Chesterfield, Missouri

This symposium will discuss new insecticidal proteins with either new insect spectrum or MOA's for controlling current Bt susceptible and resistant insects, revisions to the Bt nomenclature, structure/function analysis of proteins for determination of specificity, and regulatory considerations for the registration of these new proteins.

Presentations:

• 10:00 AM - 10:20 AM EST

  Bacterial pesticidal protein nomenclature and online resources
  

  Presenting Author: Neil Crickmore – University of Sussex

  Co-Author: Colin Berry

  Co-Author: Suresh Pannerselvam – University of Florida

  Co-Author: Ruchir Mishra – University of Florida

  Co-Author: Thomas Connor – Cardiff University

  Co-Author: Bryony C. Bonning – University of Florida
• 10:20 AM - 10:35 AM EST

  A Vip4 protein from Bacillus thuringiensis to control western corn rootworm
  

  Presenting Author: Yong Yin – Monsanto Company

  Co-Author: William J. Moar

  Co-Author: James Roberts – Bayer Crop Science

  Co-Author: Agoston Jerga – Monsanto Co.

  Co-Author: Jean-Louis Kouadio – Bayer Crop Science
• 10:35 AM - 10:50 AM EST

  Humbled by Mother Nature: Toxicity of Brevibacillus laterosporus against lepidopteran pests
  

  Presenting Author: Stephen Ford

  Co-Author: Travis Glare – Lincoln University
• 10:50 AM - 10:55 AM EST

  Break
• 10:55 AM - 11:10 AM EST

  Insecticidal proteins derived from plants
  

  Presenting Author: Jennifer Barry
• 11:10 AM - 11:25 AM EST

  Structural and functional characterization of Cry75Aa1.1, a western corn rootworm active beta-pore forming protein from Brevibacillus laterosporus
  

  Presenting Author: Agoston Jerga – Monsanto Co.

  Co-Author: Jean-Louis Kouadio – Bayer Crop Science

  Co-Author: Stephen Duff – Bayer Crop Science

  Co-Author: Michael Aikins – Kansas State University

  Co-Author: Meiying Zheng – Bayer Crop Science

  Co-Author: Timothy Rydel – Bayer Crop Science

  Co-Author: Danqi Chen – Bayer Crop Science

  Co-Author: Eric Bretsnyder – Bayer Crop Science

  Co-Author: Jun Zhang – Bayer Crop Science

  Co-Author: Jason Milligan – Bayer Crop Science

  Co-Author: Artem Evdokimov – Bayer Crop Science

  Co-Author: Jeffrey , Nageotte – Bayer Crop Science

  Co-Author: Yong Yin – Monsanto Company

  Co-Author: William J. Moar

  Co-Author: Kara Giddings – Bayer CropScience

  Co-Author: Yoonseong Park – Kansas State University

  Co-Author: Jeffrey Haas – Bayer Crop Science
• 11:25 AM - 11:40 AM EST

  Structure-function of novel western corn rootworm-active proteins
  

  Presenting Author: Mark E. Nelson – Corteva Agriscience

  Co-Author: Brad Poland – Corteva Agriscience

  Co-Author: Heather Pence – Corteva Agriscience

  Co-Author: Andrew Bowling – Corteva Agriscience

  Co-Author: Eswar Narayanan – Corteva Agriscience

  Co-Author: Albert Lu – Corteva Agriscience
• 11:40 AM - 11:55 AM EST

  Structure and function of vegetative insecticidal toxins of Bacillus thuringiensis
  

  Presenting Author: Colin Berry

  Co-Author: Matthew Byrne – University of Leeds

  Co-Author: Matthew Iadanza – University of Leeds

  Co-Author: Marcos Arribas Perez – University of Leeds

  Co-Author: Daniel Maskell – University of Leeds

  Co-Author: Rachel George – University of Leeds

  Co-Author: Emma Hesketh – University of Leeds

  Co-Author: Paul Beales – University of Leeds

  Co-Author: Marc Zack – Corteva Agriscience

  Co-Author: Husam Al-Maslookhi – Cardiff University

  Co-Author: Dafydd Jones – Cardiff University

  Co-Author: Rebecca Thompson – University of Leeds
• 11:55 AM - 12:00 PM EST

  Break
• 12:00 PM - 12:15 PM EST

  Beta-pore forming proteins from edible fungi
  

  Presenting Author: Michelle Dunstone – Monash University

  Co-Author: Bradley Spicer – Monash University

  Co-Author: Justin Lacomel – Monash University

  Co-Author: Charles Bayly-Jones
• 12:15 PM - 12:30 PM EST

  The use of bioinformatics to assess differences in insecticidal protein binding
  

  Presenting Author: Colton Kessenich – Bayer CropScience

  Co-Author: Andre Silvanovich – Bayer Crop Science
• 12:30 PM - 12:45 PM EST

  Mechanism of resistance to Vip3Aa in fall armyworm (Spodoptera frugiperda) populations from Louisiana and Texas
  

  Presenting Author: Heba Mohamed Yassen Abdelgaffar, PhD

  Co-Author: Fei Yang – Texas A&M University

  Co-Author: David L. Kerns

  Co-Author: Fangneng Huang

  Co-Author: Graham P. Head

  Co-Author: Juan Luis Jurat-Fuentes – University of Tennessee
• 12:45 PM - 1:00 PM EST

  Canadian regulatory considerations for crops expressing novel insecticidal proteins
  

  Presenting Author: Andrea Jayne Hitchon – Canadian Food Inspection Agency

  Co-Author: Sarah Davis – Canadian Food Inspection Agency

  Co-Author: Agnès Lichota – Canadian Food Inspection Agency

  Co-Author: Cécile Girard – Canadian Food Inspection Agency
• 1:00 PM - 1:05 PM EST

  Break
• 1:05 PM - 1:20 PM EST

  The intersection of MOA and Safety Assessment for novel insecticidal trait proteins
  

  Presenting Author: Frederick Walters

  Co-Author: Gerson Graser – Syngenta Crop Protection
• 1:20 PM - 1:35 PM EST

  Challenges in the ERA of new insecticidal proteins: A case study of mCry51 for Lygus control
  

  Presenting Author: Christopher R. Brown – Bayer Crop Science

  Co-Author: Peter Asiimwe – Bayer Crop Science

  Co-Author: Aqeel Ahmad – Bayer Crop Science

  Co-Author: Lieselot Bertho – Bayer Crop Science

  Co-Author: Luis Burzio – Bayer Crop Science

  Co-Author: Steven Levine, PhD

  Co-Author: Graham P. Head

  Co-Author: Pamela Bachman – Bayer Crop Science

  Co-Author: Collin Preftakes – Bayer Crop Science

  Co-Author: Geoffrey M. Mueller – Bayer CropScience LP

  Co-Author: Jennifer Fridley – Bayer Crop Science

  Co-Author: Jianguo Tan – Bayer CropScience
• 1:35 PM - 1:50 PM EST

  Regulatory considerations for the commercialization of new insecticidal technologies
  

  Presenting Author: Eric Walter Bohnenblust

  Co-Author: Amanda Pierce – US Environmental Protection Agency

  Co-Author: Alan Reynolds – US Environmental Protection Agency

  Co-Author: Kara Welch
• 1:50 PM - 2:00 PM EST

  Panel discussion